Some patients will metabolize a drug very quickly, whereas others will metabolize it slowly or not at all. In the study of pharmacogenetics, our genes can tell us how you will respond to a certain drug and if there is the potential for adverse reactions or side effects.
Pharmacogenetics is an expanding field of medicine that helps doctors and patients understand how individuals metabolize different drugs. It refers to how variation in one single gene influences the response to a single drug. Pharmacogenomics is a broader term, which studies how the whole genome can influence responses to drugs.
Pharmaceutical companies study and report on the biochemical pathways their drugs use. With so many choices available, it can be difficult for healthcare providers to be familiar with all of the data. By identifying which genetic variations you have and integrating them with information from your health history and annual prevention screen, more effective healthcare plans can be developed.
These tests will improve overall patient safety. They calculate the efficiency of a drug, recommend the quantity necessary and determine any unexpected interactions between multiple prescriptions.
TreatGxPlus is a genetic test taken by a cheek swab (inside the mouth), that looks at an individual’s response to different drug therapies by analyzing certain genes.
- Pharmacokinetic (PK) genes tell us how the body breaks down and eliminates drugs. Variations in these genes can alter typical medication processing and affect how much medication an individual might actually need.
- Pharmacodynamics (PD) genes impact how an individual might respond to a drug (for example, whether the therapy will be effective or not for a particular individual). Variations in these genes can alter drug targets in your body, such as your receptors. If an individual has more targets available, they will need a higher dose of the drug than someone who has less expression of that protein target.
Information from TreatGxPlus provides you and your physician with additional insight as to which medication and its dosage is best for you. Along with your family history and health history, your genetic predisposition will influence drug selection, necessary dosage, benefits and potential adverse effects.
WHO SHOULD BE TESTED?
- Patients taking multiple medications (polypharmacy)
- Anyone struggling to find an effective medication
- Proactive patients who want to understand how their genetic breakdown effects future prescriptions
- Individuals embarking on a new treatment plan
Information from TreatGx may also help inform treatment plans for those living with condition(s) such as:
- Atrial Fibrillation
- Bipolar 1 Disorder
- Chronic Obstructive Pulmonary Disease (COPD)
- Diabetes Mellitus Type 2
- Dyspepsia/Peptic Ulcer Disease
- Gastroesophageal Reflux Disease
- H. Pylori Eradication
- Heart Failure
- Lower Back Pain
- Neuropathic Pain
- Peripheral Arterial Disease
- Post-Myocardial Infarction
- Prevention of NSAID-Induced Ulcers
- Rheumatoid Arthritis
- Trigeminal Neuralgia
- Smoking Cessation
- Urinary Tract Infection